Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

C V F Carrington; P J Norman; R W Vaughan; E Kondeatis; D D Ramdath; K Hameed; H A F Stephens

doi:10.1046/j.1365-2370.2003.00417.x

Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

Eur J Immunogenet. 2003 Oct;30(5):375-9. doi: 10.1046/j.1365-2370.2003.00417.x.

Authors

C V F Carrington¹, P J Norman, R W Vaughan, E Kondeatis, D D Ramdath, K Hameed, H A F Stephens

Affiliation

¹ University of the West Indies, St. Augustine, Trinidad. ccarrington@fms.uwi.tt

PMID: 14641546
DOI: 10.1046/j.1365-2370.2003.00417.x

Abstract

Analysis of FcgammaRIIA alleles in Pakistanis and in Trinidadians of South Asian, African and mixed ancestry revealed no significant differences between Trinidadian South Asians and Pakistanis. H131 homozygotes were more common among Trinidadian South Asians than among Africans and those of mixed ancestry. Comparison with other populations revealed east-west geographic gradients of allele frequencies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Africa
Antigens, CD / genetics*
Asia
Gene Frequency
Humans
Polymorphism, Genetic*
Receptors, IgG / genetics*

Substances

Antigens, CD
Fc gamma receptor IIA
Fc gamma receptor IIB
Fc gamma receptor IIC
Receptors, IgG