Use of recombinant factor VIIa for bleeding in children with Glanzmann thrombasthenia

Pediatr Hematol Oncol. 2003 Sep;20(6):435-8.

Abstract

Glanzmann thrombasthenia is a very rare inherited platelet function disorder in which bleeding may be extremely difficult to stop. Recombinant factor VIIa is one of the alternative treatments for bleeding. The authors report here their experience with the use of factor VIIa, which may be useful for arresting bleeding in Glanzmann thrombasthenia.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Child
  • Circumcision, Male / adverse effects
  • Epistaxis / drug therapy
  • Epistaxis / etiology
  • Factor VII / therapeutic use*
  • Factor VIIa
  • Female
  • Hemorrhage / drug therapy*
  • Hemorrhage / etiology
  • Humans
  • Postoperative Hemorrhage / drug therapy
  • Postoperative Hemorrhage / etiology
  • Recombinant Proteins / therapeutic use*
  • Thrombasthenia / blood
  • Thrombasthenia / complications
  • Thrombasthenia / drug therapy*

Substances

  • Recombinant Proteins
  • Factor VII
  • recombinant FVIIa
  • Factor VIIa