Craniofacial dysmorphology and three-dimensional ultrasound: a prospective study on practicability for prenatal diagnosis

Prenat Diagn. 2003 Oct;23(10):810-8. doi: 10.1002/pd.681.

Abstract

Objective: The aim of this study is to compare two-dimensional and three-dimensional ultrasound for the visualization and diagnosis of craniofacial dysmorphism.

Methods: In this prospective study, we performed three-dimensional (3D) ultrasound following good-quality two-dimensional (2D) ultrasound in an at-risk population. Findings from 2D and 3D examination were noted.

Results: Our series included 41 patients. In 20 cases, 3D performed better than 2D, and in two cases 2D was more informative. In 9 cases, there was no difference between the performance of the two, and in two cases both 2D and 3D gave inadequate results. However, in 7 cases 3D images could not be obtained.

Conclusion: Although it is rarely decisive, 3D ultrasound is of interest when it comes to the precise description of craniofacial dysmorphisms and the study of the fetal ears.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Craniofacial Abnormalities / diagnostic imaging*
  • Craniofacial Abnormalities / embryology
  • Craniofacial Abnormalities / epidemiology
  • Female
  • Fetal Diseases / diagnostic imaging*
  • Fetal Diseases / embryology
  • Fetal Diseases / epidemiology
  • France / epidemiology
  • Humans
  • Predictive Value of Tests
  • Pregnancy
  • Pregnancy Trimester, Third
  • Prospective Studies
  • Ultrasonography, Prenatal*