[Tissue protection by ischemic preconditioning depends mainly on expression of heat shock protein 32]

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):251-3.
[Article in German]

Abstract

Using the hairless mouse ear skin flap model we demonstrate that HSP-32 expression has to be considered as a significant mechanism of ischemic preconditioning-induced protection of critically perfused tissue.

MeSH terms

  • Animals
  • Blood Flow Velocity / physiology
  • Graft Survival / physiology*
  • Heme Oxygenase (Decyclizing) / physiology*
  • Heme Oxygenase-1
  • Ischemic Preconditioning / methods*
  • Laser-Doppler Flowmetry
  • Membrane Proteins
  • Mice
  • Mice, Hairless
  • Microcirculation / physiopathology
  • Microsurgery
  • Surgical Flaps / blood supply*

Substances

  • Membrane Proteins
  • Heme Oxygenase (Decyclizing)
  • Heme Oxygenase-1
  • Hmox1 protein, mouse