Reticular degeneration of the retinal pigment epithelium (RDRPE) was found in 33 out of 3114 files (1.06%) of fluorescein angiography. The age distribution of the cases with RDRPE showed a peak in the 8th decade, and the average age was 73 years. No statistically significant sexual tendency was observed. Eighty five percent of cases had bilateral RDRPE. The linear, incomplete polygon type was found on the nasal quadrants in patients aged 50-70 years old. The complete polygon type was found in both nasal and temporal quadrants in patients over 70 years old. RDRPE and pigment epithelium degeneration at the posterior pole were found to be concomitant manifestations. It was concluded that RDRPE initially appears on nasal quadrants as a lineal, incomplete polygon pattern and in advanced cases complete polygon pattern appears on all quadrants of the peripheral retina.