Prenatal biochemical screening

J Reprod Med. 1992 May;37(5):403-9.

Abstract

Most fetal abnormalities occur in low-risk pregnancies. Screening techniques have been developed to help determine who in the low-risk group may actually be at high risk. Biochemical screening for chromosomal abnormalities and neutral tube defects have significantly increased their detection, but there is still considerable room for improvement.

Publication types

  • Review

MeSH terms

  • Amniocentesis / standards
  • Chorionic Gonadotropin / blood
  • Congenital Abnormalities / blood*
  • Congenital Abnormalities / diagnosis
  • Congenital Abnormalities / epidemiology
  • Estriol / blood
  • Female
  • Genetic Diseases, Inborn / blood*
  • Genetic Diseases, Inborn / diagnosis
  • Genetic Diseases, Inborn / epidemiology
  • Humans
  • Mass Screening / methods
  • Mass Screening / standards*
  • Maternal Age
  • Pregnancy
  • Prevalence
  • Sensitivity and Specificity
  • Ultrasonography, Prenatal
  • alpha-Fetoproteins / chemistry

Substances

  • Chorionic Gonadotropin
  • alpha-Fetoproteins
  • Estriol