Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin

Chem Res Toxicol. 1992 May-Jun;5(3):311-32. doi: 10.1021/tx00027a001.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aminoglycosides*
  • Animals
  • Anti-Bacterial Agents / toxicity*
  • Antibiotics, Antineoplastic / toxicity*
  • Bleomycin / toxicity*
  • DNA Damage*
  • Enediynes
  • Free Radicals
  • Humans
  • Zinostatin / toxicity*

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Antibiotics, Antineoplastic
  • Enediynes
  • Free Radicals
  • calicheamicin gamma(1)I
  • Bleomycin
  • Zinostatin