Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent beta-adrenergic agonist virtually specific for beta 3 receptors. A promising antidiabetic and antiobesity agent

J Med Chem. 1992 Aug 7;35(16):3081-4. doi: 10.1021/jm00094a025.
No abstract available

MeSH terms

  • Adipose Tissue / metabolism
  • Adrenergic beta-Agonists / metabolism
  • Adrenergic beta-Agonists / pharmacology*
  • Animals
  • Diabetes Mellitus, Type 2 / drug therapy
  • Hypoglycemic Agents / pharmacology*
  • Lipolysis / drug effects
  • Male
  • Mice
  • Mice, Obese
  • Obesity / drug therapy*
  • Substrate Specificity

Substances

  • Adrenergic beta-Agonists
  • Hypoglycemic Agents