Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia

Rev Inst Med Trop Sao Paulo. 1992 Sep-Oct;34(5):479-82. doi: 10.1590/s0036-46651992000500017.

Abstract

Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990. Two siblings living in Santa Maria, RS, developed aplastic crisis during May, 1991, when they were also diagnosed for hereditary spherocytosis. For a third child from this same family, who first developed aplastic crisis no IgM anti-B19 was detected in her sera.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Aplastic / diagnosis
  • Anemia, Aplastic / etiology*
  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / diagnosis
  • Antibodies, Viral / blood
  • Child
  • Child, Preschool
  • Erythema Infectiosum / complications*
  • Erythema Infectiosum / diagnosis
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Male
  • Parvovirus B19, Human / immunology
  • Spherocytosis, Hereditary / complications*
  • Spherocytosis, Hereditary / diagnosis

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M