A case of juvenile chronic myeloid leukemia with XX/XXX mosaicism

Turk J Pediatr. 1992 Oct-Dec;34(4):251-4.

Abstract

Cytogenetic abnormalities are rarely found in patients with juvenile chronic myelogenous leukemia (JCML). In patients with chromosomal abnormalities, chromosomes 7 and 8 are usually involved. A case of JCML with 47 XXX and a 46 XX karyotype is described and the literature is reviewed. To our knowledge, this is the first case ever to have been reported.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Female
  • Humans
  • Karyotyping
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
  • Mosaicism / diagnosis
  • Mosaicism / genetics*
  • Sex Chromosome Aberrations / diagnosis
  • Sex Chromosome Aberrations / genetics
  • X Chromosome*