[Micropolyarteritis]

Nephrologie. 1992;13(6):283-6.
[Article in French]

Abstract

Micropolyarteritis are defined as necrotizing inflammatory lesion of the wall of small vessels affecting different organs. A necrotizing crescentic glomerulonephritis without immuno-deposits is observed in the kidney, frequently involved in this microscopic form of systemic vasculitis. Micropolyarteritis are regrouped with Wegener's syndrome and isolated pauci-immune necrotizing crescentic glomerulonephritis as "ANCA-related vasculitis", whose diagnosis is assessed throw renal biopsy and prognosis dependent on immuno-suppressive treatment. Sixty-one patients treated in our nephrology department for a RPGN during these ten recent years have been retrospectively studied. Among them, twenty-five patients presented clinical and morphologic aspects compatible with the diagnosis of micropolyarteritis. We present their clinical aspects and evolution under treatment.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antibodies, Antineutrophil Cytoplasmic
  • Arteritis* / complications
  • Arteritis* / diagnosis
  • Arteritis* / immunology
  • Arteritis* / pathology
  • Arteritis* / therapy
  • Autoantibodies
  • Glomerulonephritis / etiology
  • Glomerulonephritis / pathology
  • Granulomatosis with Polyangiitis
  • Humans
  • Kidney / blood supply

Substances

  • Antibodies, Antineutrophil Cytoplasmic
  • Autoantibodies