Abstract
Data are reviewed describing hypoxemia, a newly identified feature in thalassemia. Evidence indicates platelet aggregation in the pulmonary circulation as being a key factor leading to hypoxemia and cor-pulmonale with right heart failure.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Aspirin / administration & dosage
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Aspirin / pharmacology
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Aspirin / therapeutic use
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Blood Gas Analysis
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Dipyridamole / administration & dosage
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Dipyridamole / pharmacology
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Dipyridamole / therapeutic use
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Follow-Up Studies
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Heart Failure / etiology
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Humans
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Hypoxia / blood
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Hypoxia / drug therapy
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Hypoxia / etiology*
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Platelet Aggregation*
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Pulmonary Circulation
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Pulmonary Heart Disease / etiology
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Splenectomy
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Thalassemia / complications*
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Thalassemia / surgery