Modification of surgical technique for ascending aortic atherosclerosis: impact on stroke reduction in coronary artery bypass grafting

J Thorac Cardiovasc Surg. 2003 Aug;126(2):391-400. doi: 10.1016/s0022-5223(03)00395-7.

Abstract

Objective: Use of epiaortic scanning in coronary surgery is still a matter of debate. It is unclear whether the findings obtained by epiaortic scanning lead to effective changes in surgical technique that may reduce stroke rates.

Methods: Epiaortic scanning was performed in 352 patients undergoing primary coronary artery bypass grafting before opening the pericardium using a 7.5-MHz ultrasonic probe. In the presence of moderate atherosclerosis (maximum aortic wall thickness of 3 to 5 mm), primarily single aortic crossclamping was carried out. In cases of severe sclerosis (maximum aortic wall thickness > 5 mm), aortic no-touch techniques on the beating heart were used.

Results: The degree of ascending aortic atherosclerosis was normal or mild in 151 patients (42.9%), moderate in 167 patients (47.5%), and severe in 34 patients (9.6%). The operative technique was modified in 31.1% of patients with moderate aortic sclerosis and in 91.2% of patients with severe aortic sclerosis. Perioperative mortality was 0.0% for mild disease, 3.0% for moderate disease, and 8.8% for severe disease (P =.005). Corresponding stroke rates reached 2.0%, 2.4%, and 2.9% (P =.935). Logistic regression adjusting for EuroSCORE showed that ascending aortic atherosclerosis was an independent predictor of perioperative mortality (P =.013, odds ratio 1.67, confidence interval 1.11-2.50). The influence of aortic disease on the stroke prevalence was probably due to chance (P =.935), demonstrating a potentially positive effect of operative modifications concerning stroke caused by aortic manipulation.

Conclusions: We conclude that intraoperative screening of coronary artery bypass grafting patients by epiaortic scanning can reveal useful information about the operative risk and with an aortic no-touch concept, perioperative stroke rates in high-risk patients may be lower than predicted.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Age Factors
  • Aged
  • Aorta / pathology*
  • Aorta / surgery*
  • Arteriosclerosis / epidemiology
  • Arteriosclerosis / surgery*
  • Austria / epidemiology
  • Coronary Artery Bypass*
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / epidemiology
  • Myocardial Infarction / etiology
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Predictive Value of Tests
  • Prevalence
  • Proportional Hazards Models
  • Risk Factors
  • Risk Reduction Behavior
  • Severity of Illness Index
  • Stroke / epidemiology
  • Stroke / etiology
  • Treatment Outcome