Abstract
A case of bacteremia due to high-level-vancomycin- (MIC = 64 micrograms/ml) and high-level-teicoplanin- (MIC = 32 micrograms/ml) resistant Enterococcus gallinarum is described. Both genes, van C1 and van A, respectively conferring natural low-level resistance and acquired high-level resistance to vancomycin, were found in the enterococcal genoma. The present is the first report of an E. gallinarum isolate showing the van A genotype in Argentina.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Argentina / epidemiology
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Bacteremia / drug therapy
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Bacteremia / microbiology*
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Bacterial Proteins / analysis
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Bacterial Proteins / genetics
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Carbon-Oxygen Ligases / analysis
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Carbon-Oxygen Ligases / genetics
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Drug Resistance, Multiple, Bacterial* / genetics
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Enterococcus / classification
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Enterococcus / drug effects
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Enterococcus / genetics
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Enterococcus / isolation & purification*
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Fatal Outcome
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Gram-Positive Bacterial Infections / drug therapy
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Gram-Positive Bacterial Infections / microbiology*
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Humans
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Male
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Middle Aged
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Postoperative Complications / microbiology
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Teicoplanin / pharmacology*
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Vancomycin / pharmacology*
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Vancomycin Resistance / genetics
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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VanA ligase, Bacteria
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Teicoplanin
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Vancomycin
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Carbon-Oxygen Ligases