[Isolation of a kind of endophytic fungus which can produce taxol compounds]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2001 Dec;23(6):642-4.
[Article in Chinese]

Abstract

Objective: To isolate a kind of endophytic fungus which can produce taxol compounds from the bark of Taxus Cuspidata Sieb et Zucc.

Methods: Endophytic fungus was isolated from the bark of Taxus Cuspidata Sieb et Zucc by aseptic techniques and the analysis of the culture fluid from the fermentation of fungus was carried out by high performance liquid chromatography (HPLC).

Results: Endophytic fungus was obtained from the bark of Taxus Cuspidata Sieb et Zucc and the chemical analysis showed that the culture of fungus contain taxol compounds.

Conclusion: Endophytic fungus which can produce taxol compounds exists in the bark of Taxus Cuspidata Sieb et Zucc.

Publication types

  • English Abstract

MeSH terms

  • Chromatography, High Pressure Liquid
  • Fungi / isolation & purification*
  • Fungi / metabolism
  • Paclitaxel / analysis
  • Paclitaxel / biosynthesis
  • Plant Bark / microbiology
  • Taxus / microbiology*

Substances

  • Paclitaxel