Prolonged asystole during head-up tilt testing with clomipramine infusion

Europace. 2003 Jul;5(3):313-5. doi: 10.1016/s1099-5129(03)00028-x.

Abstract

This case report describes a patient with a history of neurocardiogenic syncope, who had had a negative head-up tilt test with isoprenaline, but he experienced a prolonged asystole during a head-up tilt test with clomipramine (serotonin reuptake inhibitor) 24 h later. This patient was successfully treated with fluoxetine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Clomipramine / administration & dosage
  • Clomipramine / adverse effects*
  • Heart Arrest / etiology*
  • Humans
  • Infusions, Intravenous
  • Male
  • Selective Serotonin Reuptake Inhibitors / administration & dosage
  • Selective Serotonin Reuptake Inhibitors / adverse effects*
  • Syncope, Vasovagal / diagnosis
  • Tilt-Table Test / adverse effects*
  • Time Factors

Substances

  • Serotonin Uptake Inhibitors
  • Clomipramine