Multidisciplinary treatment has improved the clinician's ability to restore patients with partial anodontia using implant, orthodontic, and restorative disciplines for aesthetics and functionality. When considering biological principles and--in particular--patient anxiety, the use of a combination treatment approach may facilitate predictable success. When partial anodontia is evident, the primary rehabilitative options include fixed prostheses, recontouring of teeth, or placement of a single implant. This article discusses treatment planning for restoration of partial bilateral anodontia and illustrates the implant placement in association with orthodontic and restorative procedures.