A total of 460 Anopheles funestus s.l. was collected inside human dwellings in Mwea, central Kenya. Of the 414 specimens that were positively identified, 1 was Anopheles leesoni and the others were Anopheles parensis. None of the 373 specimens tested were positive for Plasmodium falciparum or Plasmodium malariae sporozoites by enzyme-linked immunosorbent assay (ELISA). Of the 139 ELISA blood-meal-positive specimens, 82.01% and 1.44% had fed on cattle and humans, respectively. These results are discussed in the context of implications for malaria control through vector-control strategies.