Graft-versus-host disease in lung transplantation: 4 case reports and literature review

J Heart Lung Transplant. 2003 Jun;22(6):691-7. doi: 10.1016/s1053-2498(02)00811-2.

Abstract

Graft-versus-host disease (GVHD) is uncommon in lung transplant recipients despite the transfer of a significant amount of donor-derived lymphoid tissue and cells. It is associated with significant morbidity and a high mortality rate. We describe 4 cases of GVHD encountered over a 17-year period and review the literature about this peculiar pathology.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Female
  • Graft Rejection / diagnosis
  • Graft Rejection / etiology
  • Graft Rejection / immunology
  • Graft vs Host Disease / diagnosis
  • Graft vs Host Disease / etiology*
  • Graft vs Host Disease / immunology
  • Heart-Lung Transplantation
  • Histocompatibility / immunology
  • Histocompatibility Testing
  • Humans
  • Immunity, Cellular / immunology
  • Immunosuppressive Agents / therapeutic use
  • Lung Transplantation*
  • Major Histocompatibility Complex / immunology
  • Male
  • Middle Aged

Substances

  • Immunosuppressive Agents