Inhibition of farnesyl-protein transferase by gliotoxin and acetylgliotoxin

J Antibiot (Tokyo). 1992 Nov;45(11):1802-5. doi: 10.7164/antibiotics.45.1802.
No abstract available

MeSH terms

  • Acetylation
  • Alkyl and Aryl Transferases*
  • Amino Acid Sequence
  • Cell Line
  • Gliotoxin / isolation & purification
  • Gliotoxin / pharmacology*
  • Humans
  • Molecular Sequence Data
  • Molecular Structure
  • Monocytes / enzymology
  • Mycotoxins / isolation & purification
  • Mycotoxins / pharmacology*
  • Oncogene Protein p21(ras) / metabolism
  • Peptide Fragments / chemistry
  • Peptide Fragments / metabolism
  • Transferases / antagonists & inhibitors*

Substances

  • Mycotoxins
  • Peptide Fragments
  • Gliotoxin
  • Transferases
  • Alkyl and Aryl Transferases
  • p21(ras) farnesyl-protein transferase
  • Oncogene Protein p21(ras)