Heterogeneity of admission history among patients with bipolar disorder

J Affect Disord. 2003 Jul;75(2):163-70. doi: 10.1016/s0165-0327(02)00041-1.

Abstract

Background: Patients on a first admission for bipolar disorder often have a history of other psychiatric diagnoses for previous admissions.

Aims: The current study examines the time course and diagnoses of psychiatric admissions prior and subsequent to a first hospitalisation for a diagnosis of bipolar disorder.

Method: The prior admission histories (over the period 1965-1989) of 1167 patients who had been hospitalised in state mental health facilities with their first admission with diagnosis of bipolar disorder between 1983 and 1989 were examined.

Results: A total of 542 (46.4%) patients had at least one previous hospitalisation with a psychiatric diagnosis other than bipolar disorder. Two prominent groups emerged; one group which had primarily a history of prior admissions with diagnoses of depression over 1-3 years, and a second which mainly had previous admissions for schizophrenia, over a period longer than for those with a primarily depressive history. The group with a history of schizophrenia was significantly younger and had a greater number of admissions prior to the first bipolar disorder diagnosis than the depression group.

Limitations: This was a record-based study which did not examine cases which were not hospitalised.

Conclusions: There appeared to be three distinct patterns of prior presentations in those patients admitted with a diagnosis of bipolar disorder.

MeSH terms

  • Adult
  • Age of Onset
  • Bipolar Disorder / psychology
  • Bipolar Disorder / therapy*
  • Depressive Disorder / diagnosis
  • Female
  • Humans
  • Male
  • Medical History Taking*
  • Middle Aged
  • Patient Admission / statistics & numerical data*
  • Retrospective Studies
  • Risk Factors
  • Schizophrenia / diagnosis