A caution on the use of murine hemophilia models for comparative immunogenicity studies of FVIII products with different protein compositions

MeSH terms

• Animals
• Disease Models, Animal*
• Factor VIII / immunology*
• Factor VIII / standards
• Factor VIII / therapeutic use
• Hemophilia A / drug therapy*
• Hemophilia A / immunology
• Humans
• Immunity
• Mice
• Proteins