Abstract
Described here are two cases of cerebral aspergillosis successfully treated with voriconazole after the failure of first-line treatment with amphotericin B deoxycholate. In both cases, clinical and radiological cure was achieved within 6 weeks. Voriconazole should be considered as first-line therapy for cerebral aspergillosis.
MeSH terms
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Administration, Oral
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Antifungal Agents / administration & dosage*
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Brain Diseases / diagnosis
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Brain Diseases / drug therapy*
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Female
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Follow-Up Studies
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Humans
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Infusions, Intravenous
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neuroaspergillosis / diagnosis
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Neuroaspergillosis / drug therapy*
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Pyrimidines / administration & dosage*
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Treatment Outcome
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Triazoles / administration & dosage*
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Voriconazole
Substances
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Antifungal Agents
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Pyrimidines
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Triazoles
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Voriconazole