Diagnosis and management of hepatic copper accumulation in a Skye terrier

J Small Anim Pract. 2003 Feb;44(2):85-9. doi: 10.1111/j.1748-5827.2003.tb00126.x.

Abstract

A one-year-old, neutered female Skye terrier presented with anorexia, vomiting, seizures and ascites. Portal venography demonstrated the presence of multiple acquired portosystemic shunts. Hepatic biopsy confirmed the presence of copper accumulation and fibrosis. Treatment included ursodeoxycholic acid therapy, colchicine and oral zinc. To the authors' knowledge, this is the first case report detailing successful management of Skye terrier hepatopathy.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Ascites / etiology
  • Ascites / veterinary
  • Colchicine / administration & dosage
  • Copper / metabolism*
  • Dog Diseases / diagnosis*
  • Dog Diseases / diagnostic imaging
  • Dog Diseases / drug therapy*
  • Dog Diseases / pathology
  • Dogs
  • Drug Therapy, Combination
  • Female
  • Liver / blood supply
  • Liver Diseases / complications
  • Liver Diseases / diagnosis
  • Liver Diseases / drug therapy
  • Liver Diseases / veterinary*
  • Radiography
  • Seizures / etiology
  • Seizures / veterinary
  • Ultrasonography
  • Ursodeoxycholic Acid / administration & dosage
  • Vomiting / etiology
  • Vomiting / veterinary
  • Zinc / administration & dosage

Substances

  • Ursodeoxycholic Acid
  • Copper
  • Zinc
  • Colchicine