Lymphoid blast crisis of chronic myelogenous leukemia occurring more than 11 years after receiving an allogeneic bone marrow transplant for chronic myelogenous leukemia in myeloid blast crisis at onset

K Fukuno; H Tsurumi; T Yamada; M Oyama; T Matsuyama; S Terakura; Y Kodera; H Moriwaki

doi:10.1038/sj.bmt.1703820

Lymphoid blast crisis of chronic myelogenous leukemia occurring more than 11 years after receiving an allogeneic bone marrow transplant for chronic myelogenous leukemia in myeloid blast crisis at onset

Bone Marrow Transplant. 2003 Feb;31(3):211-3. doi: 10.1038/sj.bmt.1703820.

Authors

K Fukuno¹, H Tsurumi, T Yamada, M Oyama, T Matsuyama, S Terakura, Y Kodera, H Moriwaki

Affiliation

¹ Department of Internal Medicine, Kisogawa Hospital, Aichi, Japan.

PMID: 12621483
DOI: 10.1038/sj.bmt.1703820

Abstract

A 25-year-old male developed lymphoid blast crisis (BC) of chronic myelogenous leukemia (CML) more than 11 years after receiving an allogeneic bone marrow transplant (alloBMT) for CML with myeloid BC at presentation from his HLA-identical brother. The lymphoid BC of CML probably occurred without a preceding chronic phase of CML. This case illustrates the difficulties involved in determining the appropriate length of follow-up after alloBMT.

Publication types

Case Reports

MeSH terms

Adult
Blast Crisis / diagnosis
Blast Crisis / pathology*
Bone Marrow Transplantation*
Follow-Up Studies
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy*
Male
Siblings
Time Factors
Transplantation Chimera
Transplantation, Homologous