Objective: The regulatory effects of total diterpene of Rabdosia macrocalyx (Dunn) Hara on immune function were studied.
Methods: The experimental immunosuppressive mouse models were induced by injection of cyclophosphamide.
Results: The index of thymus gland and spleen in normal and immunosuppressive mice were increased significantly. So were the level of hemolysin in serum when 50 mg/kg total diterpene were given. Delayed hypersensivity were also enhanced at the same condition. But there didn't show any change in carbon clearance test.
Conclusion: Total diterpene of Rabdosia macrocalyx (Dunn) Hara possesses obvious regulatory action on immune function in mice.