Objective: To study the responsibilities and the clinical applications of auditory event-related response P300 recorded with active and passive modes in normal young adults.
Method: P300s were recorded with active and passive modes, that is, to count and not to count the numbers of target stimuli during measuring respectively, in young adults as subjects. The waveforms, latencies and amplitudes of P300 were analyzed.
Result: The resemble P300 in waveform and responsibility could be recorded with active and passive mode. There were some differential responsibilities between active and passive recording modes, which the latencies in active mode were shorter than the ones in passive mode, the amplitude of N1-P2 in active mode was lower than the one in passive mode, nevertheless, the amplitude of N2-P3 in active mode was significantly higher than the one in passive mode.
Conclusion: The resemble P300 in waveform and responsibility could be recorded with active and passive mode. The differences of latencies and amplitudes between two modes demonstrated that the responsibility of P300 was related to the recognition process of auditory center. On the other hand, the passive recording mode of P300 is a way to measure for the uncooperative subjects.