HIV update 2002: delaying treatment to curb rising resistance

Cleve Clin J Med. 2002 Dec;69(12):995-9. doi: 10.3949/ccjm.69.12.995.

Abstract

The recommendation for HIV antiretroviral therapy is changing from "treat early, treat hard" to "treat a little later, treat hard" as more toxicities of the drugs are recognized. Drug-resistant HIV is becoming a serious problem, even in treatment-naive patients. For HIV patients with organ failure, transplantation is increasingly an option.

Publication types

  • Review

MeSH terms

  • AIDS Vaccines / therapeutic use
  • Antiretroviral Therapy, Highly Active / adverse effects
  • Antiretroviral Therapy, Highly Active / trends*
  • Developing Countries
  • Drug Resistance, Viral*
  • HIV Infections / complications
  • HIV Infections / drug therapy*
  • HIV Infections / mortality
  • HIV Infections / prevention & control
  • HIV-1 / physiology*
  • Humans
  • Liver Failure / etiology
  • Liver Failure / surgery
  • Neoplasms / etiology
  • Renal Insufficiency / etiology
  • Renal Insufficiency / surgery
  • Transplantation, Homologous / trends

Substances

  • AIDS Vaccines