Abstract
While the research of hypoxic-ischemic injury to the central nervous system has been focused on neurons, astrocytes are also critically involved in and contribute to the hypoxic-ischemic process. The role these cells play appears to be more and more important. There are considerable progress in characterizing the pathophysiological alterations of these cells during hypoxic-ischemic brain damage.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Astrocytes / metabolism
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Astrocytes / pathology
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Astrocytes / physiology*
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Cell Hypoxia
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Cells, Cultured
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Glutamic Acid / metabolism
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Humans
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Hypoxia-Ischemia, Brain / metabolism
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Hypoxia-Ischemia, Brain / pathology
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Hypoxia-Ischemia, Brain / physiopathology*
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Nitric Oxide / metabolism
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Receptors, N-Methyl-D-Aspartate / metabolism
Substances
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Receptors, N-Methyl-D-Aspartate
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Nitric Oxide
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Glutamic Acid