Abstract
Three new dimeric naphthopyrones, asperpyrones A (1), B (2), and C (3), together with two known compounds, fonsecinone A (4) and aurasperone A (5), have been isolated from okara that was fermented with Aspergillus niger JV-33-48. Compounds 1, 4, and 5 showed inhibitory activity on Taq DNA polymerase.
MeSH terms
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Aspergillus niger / chemistry*
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Base Sequence
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification*
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Enzyme Inhibitors / pharmacology
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Japan
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Molecular Structure
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Naphthalenes / chemistry
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Naphthalenes / isolation & purification*
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Naphthalenes / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Pyrones / chemistry
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Pyrones / isolation & purification*
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Pyrones / pharmacology
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Taq Polymerase / antagonists & inhibitors*
Substances
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Enzyme Inhibitors
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Naphthalenes
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Pyrones
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Taq Polymerase