Combined modality treatment of Ewing's sarcoma of the maxilla

Head Neck. 2003 Feb;25(2):168-72. doi: 10.1002/hed.10156.

Abstract

Background: Primary bone sarcomas arising in osseous structures of the head and neck are rare. These tumors are often incompletely resected and treated with radiotherapy for local control.

Methods: We report a case of a 9-year-old girl with a maxillary Ewing's sarcoma. This patient was successfully treated with neoadjuvant chemotherapy followed by surgical resection and prosthetic reconstruction of the primary site. The surgical approach that was used consisted of a subtotal maxillectomy by means of a facial degloving approach, sparing the orbital contents and the inferior orbital rim and orbital floor.

Results: This approach produced excellent cosmetic, functional, and oncologic outcome. The patient remains without evidence of disease recurrence more than 4 years after surgery.

Conclusions: This case illustrates a novel surgical approach to the resection of a maxillary Ewing's sarcoma and highlights the need for a multidisciplinary team approach to the management of head and neck sarcomas in children.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chemotherapy, Adjuvant
  • Child
  • Female
  • Humans
  • Maxilla / surgery
  • Maxillary Neoplasms / drug therapy*
  • Maxillary Neoplasms / surgery*
  • Maxillofacial Prosthesis
  • Neoadjuvant Therapy
  • Sarcoma, Ewing / drug therapy*
  • Sarcoma, Ewing / surgery*