Clinical blood flow quantification with segmented k-space magnetic resonance phase velocity mapping

J Magn Reson Imaging. 2003 Jan;17(1):65-71. doi: 10.1002/jmri.10231.

Abstract

Purpose: To evaluate the accuracy of segmented k-space magnetic resonance phase velocity mapping (PVM) in quantifying aortic blood flow from through-plane velocity measurements.

Materials and methods: Two segmented PVM schemes were evaluated, one with seven lines per segment (seg-7) and one with nine lines per segment (seg-9), in twenty patients with cardiovascular disease. A non-segmented (non-seg) PVM acquisition was also performed to provide the reference data.

Results: There was agreement between the aortic flow curves acquired with segmented and non-segmented PVM. The calculated systolic and total flow volume per cycle from the seg-7 and the seg-9 scans correlated and agreed with the flow volumes from the non-seg scans (differences < 5%). Sign tests showed that there were no statistically significant differences (P-values > 0.05) between the segmented and the non-segmented PVM measurements [corrected]. Seg-9, which was the fastest among the three sequences, provided adequate spatial and temporal resolution (> 10 phases per cycle).

Conclusion: Segmented k-space PVM shows great clinical potential in blood flow quantification.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aorta / pathology*
  • Blood Flow Velocity / physiology
  • Blood Volume / physiology*
  • Cardiovascular Diseases / pathology*
  • Cardiovascular Diseases / physiopathology*
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Regression Analysis