Choline starvation induces the gene licD2 in Streptococcus pneumoniae

Bhushan V Desai; Harvard Reiter; Donald A Morrison

doi:10.1128/JB.185.1.371-373.2003

Choline starvation induces the gene licD2 in Streptococcus pneumoniae

J Bacteriol. 2003 Jan;185(1):371-3. doi: 10.1128/JB.185.1.371-373.2003.

Authors

Bhushan V Desai¹, Harvard Reiter, Donald A Morrison

Affiliation

¹ Laboratory for Molecular Biology, Department of Biological Sciences, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA.

Abstract

Mutant strains of Streptococcus pneumoniae were constructed to monitor the regulation of three dispersed genes known or predicted to act in choline metabolism. One gene (licD2) was regulated in response to choline deprivation over a 30-fold range. The other two (SP1860 and licC) responded little if at all to the same challenge.

MeSH terms

Bacterial Proteins / genetics*
Bacterial Proteins / metabolism*
Choline / metabolism*
Culture Media
Gene Expression Regulation, Bacterial*
Humans
Streptococcus pneumoniae / genetics
Streptococcus pneumoniae / physiology*

Substances

Bacterial Proteins
Culture Media
LicD2 protein, Streptococcus pneumoniae
Choline