Morphometric change analysis of the optic nerve head in unilateral disk hemorrhage cases

Am J Ophthalmol. 2002 Dec;134(6):920-2. doi: 10.1016/s0002-9394(02)01791-9.

Abstract

Purpose: To measure the changes in optic disk morphology after unilateral disk hemorrhage and to compare the changes between eyes.

Design: Observational case series.

Methods: Ten glaucoma patients who had a unilateral disk hemorrhage were enrolled. The baseline measurements obtained by Heidelberg Retina Tomograph (HRT) were performed on both eyes when a disk hemorrhage was detected, and the second measurements were done after an average of 32 +/- 19 months. The amount of change and the percent change in the HRT parameters from the baseline measurements of the hemorrhagic eyes were compared with those of the contralateral nonhemorrhagic eyes.

Results: The reduction in the neuroretinal rim area and the decrease in volume were significantly greater in the octant with the disk hemorrhage than measured in the contralateral eyes (P =.002, Wilcoxon signed rank test).

Conclusions: This study demonstrated quantitatively that the progression of optic disk damage in glaucoma is faster in eyes with disk hemorrhage than in eyes without disk hemorrhage.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Progression
  • Female
  • Glaucoma, Open-Angle / complications*
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Optic Disk / pathology*
  • Optic Nerve Diseases / diagnosis*
  • Prospective Studies
  • Retinal Hemorrhage / complications*
  • Tomography