Abstract
We evaluated a new immunoblot assay (Helicoblot 2.1) for Helicobacter pylori infection and CagA and VacA status by using serum samples from 222 patients. The test accurately detected H. pylori infection and VacA status, but improvements in the interpretation criteria are required before it can be recommended for determination of CagA status.
Publication types
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Evaluation Study
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antibodies, Bacterial / immunology
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Antibodies, Monoclonal / immunology
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Antigens, Bacterial*
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Bacterial Proteins / analysis*
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Helicobacter Infections / immunology
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Helicobacter pylori / pathogenicity*
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Humans
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Immunoblotting
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Predictive Value of Tests
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Sensitivity and Specificity
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Virulence
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Virulence Factors / analysis*
Substances
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Antibodies, Bacterial
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Antibodies, Monoclonal
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Antigens, Bacterial
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Bacterial Proteins
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VacA protein, Helicobacter pylori
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Virulence Factors
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cagA protein, Helicobacter pylori