Abstract
A child with advanced stage large cell lymphoma in remission developed overwhelming, irreversible anthracycline cardiac toxicity incompatible with life early in her treatment course. The medical complexities and ethical issues concerning a decision to proceed with orthotopic heart transplantation are discussed.
MeSH terms
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Antibiotics, Antineoplastic / adverse effects*
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Antineoplastic Agents / adverse effects*
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Child
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Doxorubicin / adverse effects*
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Female
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Heart / drug effects
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Heart Diseases / chemically induced*
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Heart Diseases / surgery
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Heart Transplantation*
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Humans
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Lymphoma, B-Cell / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
Substances
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Antibiotics, Antineoplastic
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Antineoplastic Agents
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Doxorubicin