Endothelin receptor antagonists and cerebral vasospasm: an update

Michael Chow; Aaron S Dumont; Neal F Kassell

Endothelin receptor antagonists and cerebral vasospasm: an update

Neurosurgery. 2002 Dec;51(6):1333-41; discussion 1342.

Authors

Michael Chow¹, Aaron S Dumont, Neal F Kassell

Affiliation

¹ Department of Neurosurgery, University of Virginia, Charlottesville, Virginia22908-0212, USA.

PMID: 12445337

Abstract

THIS REVIEW UPDATES: the current status of endothelin receptor antagonists in the treatment of cerebral vasospasm. Recent preclinical and clinical studies are reviewed, as well as clinical trials for other medical indications. Some of the newer endothelin receptor antagonists are also examined.

Publication types

Review

MeSH terms

Animals
Endothelin Receptor Antagonists*
Endothelins / metabolism
Humans
Receptors, Endothelin / metabolism
Vasospasm, Intracranial / drug therapy*
Vasospasm, Intracranial / metabolism
Vasospasm, Intracranial / physiopathology

Substances

Endothelin Receptor Antagonists
Endothelins
Receptors, Endothelin