External anogenital condylomas are the clinical expression of a human papillomavirus mucosal infection. However, only a small proportion of patients infected by this virus will express the disease. Nevertheless, this dermatitis remains one of the most prevalent of sexually transmitted diseases and poses problems in its management. These problems are centered on phenomena of viral latency, which do not permit one to guarantee the cure of the patient, and the absence of specific anti-viral treatment. This article proposes to review the status of external anogenital condylomas. Inspired by recently published experts' recommendations, it emphasizes the problems encountered in daily practice by proposing coherent practical approaches: better understanding of the disease and contamination, assessment of the lesions, the problems related to immunodepression, the psychological approach and current therapeutic possibilities.