Unusual presentation of carcinomatous meningitis: case report and review of typical CSF findings

Neurol Res. 2002 Oct;24(7):652-4. doi: 10.1179/016164102101200708.

Abstract

This paper describes a previously unreported clinical onset of carcinomatous meningitis with bilateral deafness. Typical changes in the cerebrospinal fluid aside from positive cytology findings are reviewed. In cases of suspected carcinomatous meningitis the clustering of increased CSF protein, lactate, decreased glucose, and a high opening pressure is suggestive of the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast Neoplasms / pathology*
  • Carcinoma / cerebrospinal fluid*
  • Carcinoma / secondary*
  • Cerebellar Neoplasms / metabolism
  • Cerebrospinal Fluid / cytology
  • Cerebrospinal Fluid / metabolism
  • Cranial Nerve Diseases / etiology
  • Cranial Nerve Diseases / pathology
  • Cranial Nerve Diseases / physiopathology
  • Female
  • Hearing Loss, Sensorineural / etiology
  • Hearing Loss, Sensorineural / pathology
  • Hearing Loss, Sensorineural / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / cerebrospinal fluid*
  • Meningeal Neoplasms / secondary*