The first orally active low molecular weight agonists for the LH receptor: thienopyr(im)idines with therapeutic potential for ovulation induction

Chembiochem. 2002 Oct 4;3(10):1023-6. doi: 10.1002/1439-7633(20021004)3:10<1023::AID-CBIC1023>3.0.CO;2-9.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • CHO Cells / metabolism
  • Cricetinae
  • Estradiol / chemical synthesis
  • Female
  • Humans
  • Leydig Cells / chemistry
  • Leydig Cells / drug effects
  • Male
  • Mice
  • Molecular Weight
  • Ovulation Induction / methods*
  • Ovum / drug effects
  • Pyridines / chemical synthesis*
  • Pyridines / chemistry
  • Pyridines / pharmacology*
  • Pyrimidines / chemical synthesis*
  • Pyrimidines / chemistry
  • Pyrimidines / pharmacology*
  • Receptors, FSH / drug effects
  • Receptors, LH / agonists*
  • Receptors, LH / metabolism
  • Receptors, LH / therapeutic use
  • Testosterone / biosynthesis
  • Thiophenes / chemical synthesis*
  • Thiophenes / chemistry
  • Thiophenes / pharmacology*

Substances

  • Org 41841
  • Pyridines
  • Pyrimidines
  • Receptors, FSH
  • Receptors, LH
  • Thiophenes
  • thienopyridine
  • Testosterone
  • Estradiol