Abstract
For DNA differential diagnosis of human Taenia cestodes, a base excision sequence scanning thymine-base method using the cytochrome c oxidase subunit I and cytochrome b genes as targets was used. The characteristic thymine-base peak profiles provide four distinct types, unique for T. saginata, T. asiatica, and two genotypes of T. solium. This approach provides a useful tool for the identification and diagnosis of human taeniid cestodes without DNA sequencing if nucleotide sequence databases are available.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cytochrome b Group / genetics
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DNA, Helminth / analysis*
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DNA, Mitochondrial / analysis*
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Electron Transport Complex IV / genetics
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Humans
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Taenia saginata / enzymology
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Taenia saginata / genetics
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Taenia saginata / isolation & purification
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Taenia solium / enzymology
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Taenia solium / genetics
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Taenia solium / isolation & purification
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Taeniasis / diagnosis*
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Taeniasis / parasitology
Substances
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Cytochrome b Group
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DNA, Helminth
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DNA, Mitochondrial
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Electron Transport Complex IV