A general, efficient, and inexpensive catalyst system for the coupling of aryl iodides and thiols

Fuk Yee Kwong; Stephen L Buchwald

doi:10.1021/ol0266673

A general, efficient, and inexpensive catalyst system for the coupling of aryl iodides and thiols

Org Lett. 2002 Oct 3;4(20):3517-20. doi: 10.1021/ol0266673.

Authors

Fuk Yee Kwong¹, Stephen L Buchwald

Affiliation

¹ Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

PMID: 12323058
DOI: 10.1021/ol0266673

Abstract

An efficient copper-catalyzed carbon-sulfur bond formation reaction was developed. This method is particularly noteworthy given its experimental simplicity, high generality, and exceptional level of functional group toleration and the low cost of the catalyst system. [reaction: see text]

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Catalysis
Chemistry, Organic / economics*
Copper / chemistry
Iodides / chemical synthesis
Iodides / chemistry*
Molecular Structure
Sulfhydryl Compounds / chemical synthesis
Sulfhydryl Compounds / chemistry*

Substances

Iodides
Sulfhydryl Compounds
Copper

Grants and funding

GM 58160/GM/NIGMS NIH HHS/United States