Tribolium Hox genes repress antennal development in the gnathos and trunk

Mol Phylogenet Evol. 2002 Sep;24(3):384-7. doi: 10.1016/s1055-7903(02)00205-1.

Abstract

Evidence from Drosophila suggests that Hox genes not only specify regional identity, but have the additional function of repressing antennal development within their normal domains. This is dramatically demonstrated by a series of Hox mutants in the red flour beetle, Tribolium castaneum, and is likely an ancient function of Hox genes in insects.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Body Patterning
  • Coleoptera / embryology*
  • Coleoptera / genetics*
  • Evolution, Molecular
  • Homeodomain Proteins / genetics*
  • Homeodomain Proteins / physiology*
  • Mutation
  • Phenotype
  • Tribolium / genetics*

Substances

  • Homeodomain Proteins