Orthogonal assembly of nanoparticle building blocks on dip-pen nanolithographically generated templates of DNA

Angew Chem Int Ed Engl. 2001;40(16):3071-3. doi: 10.1002/1521-3773(20010817)40:16<3071::AID-ANIE3071>3.0.CO;2-S.

Abstract

Nanoscale construction work with DNA: Dip-pen nanolithography (DPN) is used to generate nanostructures which can be subsequently functionalized with oligonucleotides a' and b' and used to assemble, in an orthogonal manner, gold nanoparticles (a, b in scheme) functionalized with sequences complementary to the DPN-generated structures.

Keywords: DNA recognition; gold; monolayers; nanolithography; nanostructures; self-assembly.