Combinatorial and rational strategies to develop nonpeptidic alpha4beta7-integrin antagonists from cyclic peptides

Angew Chem Int Ed Engl. 2002 Aug 16;41(16):3007-11. doi: 10.1002/1521-3773(20020816)41:16<3007::AID-ANIE3007>3.0.CO;2-3.
No abstract available

MeSH terms

  • Combinatorial Chemistry Techniques / methods*
  • Drug Design
  • Integrins / antagonists & inhibitors*
  • Molecular Conformation
  • Molecular Structure
  • Peptides, Cyclic / chemical synthesis*
  • Peptides, Cyclic / pharmacology*

Substances

  • Integrins
  • Peptides, Cyclic
  • integrin alpha4beta7