Characterization of ISRgn1, a novel insertion sequence of the IS3 family isolated from a bacteriocin-negative mutant of Ruminococcus gnavus E1

Appl Environ Microbiol. 2002 Aug;68(8):4136-9. doi: 10.1128/AEM.68.8.4136-4139.2002.

Abstract

ISRgn1, an insertion sequence of the IS3 family, has been identified in the genome of a bacteriocin-negative mutant of Ruminococcus gnavus E1. The copy number of ISRgn1 in R. gnavus E1, as well as its distribution among phylogenetically E1-related strains, has been determined. Results obtained suggest that ISRgn1 is not indigenous to the R. gnavus phylogenetic group but that it can transpose in this bacterium.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria, Anaerobic / genetics*
  • Bacteria, Anaerobic / metabolism
  • Bacteriocins / metabolism*
  • Base Sequence
  • DNA Transposable Elements*
  • Gene Dosage
  • Gram-Positive Bacteria / genetics*
  • Gram-Positive Bacteria / metabolism
  • Molecular Sequence Data
  • Mutation*
  • Sequence Analysis, DNA

Substances

  • Bacteriocins
  • DNA Transposable Elements

Associated data

  • GENBANK/AF320327