Recent heart failure trials of neurohormonal modulation (OVERTURE and ENABLE): approaching the asymptote of efficacy?

J Card Fail. 2002 Jun;8(3):124-7. doi: 10.1054/jcaf.2002.126486.
No abstract available

MeSH terms

  • Aged
  • Angiotensin-Converting Enzyme Inhibitors / pharmacology
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
  • Bosentan
  • Clinical Trials as Topic
  • Enalapril / pharmacology
  • Enalapril / therapeutic use
  • Endothelin Receptor Antagonists*
  • Female
  • Heart Failure / drug therapy*
  • Heart Failure / physiopathology
  • Humans
  • Male
  • Metalloendopeptidases / antagonists & inhibitors*
  • Middle Aged
  • Neurotransmitter Agents / physiology
  • Pyridines / pharmacology
  • Pyridines / therapeutic use*
  • Sulfonamides / therapeutic use*
  • Thiazepines / pharmacology
  • Thiazepines / therapeutic use*
  • Treatment Outcome

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Endothelin Receptor Antagonists
  • Neurotransmitter Agents
  • Pyridines
  • Sulfonamides
  • Thiazepines
  • omapatrilat
  • Enalapril
  • Metalloendopeptidases
  • Bosentan