A novel germline point mutation, c.2304 G-->T, in codon 768 of the RET proto-oncogene in a patient with medullary thyroid carcinoma

Am J Med Genet. 2002 Jun 1;110(1):85-7. doi: 10.1002/ajmg.10399.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Carcinoma, Medullary / genetics
  • Carcinoma, Medullary / pathology*
  • Codon / genetics*
  • DNA / chemistry
  • DNA / genetics
  • DNA Mutational Analysis
  • Drosophila Proteins*
  • Family Health
  • Female
  • Germ-Line Mutation*
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Point Mutation
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-ret
  • Receptor Protein-Tyrosine Kinases / genetics*
  • Thyroid Neoplasms / genetics
  • Thyroid Neoplasms / pathology*

Substances

  • Codon
  • Drosophila Proteins
  • MAS1 protein, human
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins
  • DNA
  • Proto-Oncogene Proteins c-ret
  • Receptor Protein-Tyrosine Kinases
  • Ret protein, Drosophila