A case of flare syndrome

Infez Med. 2001 Sep;9(3):176-7.

Abstract

The authors describe a case of severe CMV retinitis in a young adult AIDS patient who recovered following first a course of ganciclovir and then HAART. Six months after the initial episode while still under successful HAART, the patient developed an acute episode of retinitis despite a persistent significant improvement in the immunological picture and a very low level of CMV reactivation. The acute episode can be related to an enhanced individual reactivity to minor CMV replication.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / etiology*
  • Acute Disease
  • Adult
  • Antiretroviral Therapy, Highly Active*
  • Antiviral Agents / therapeutic use
  • CD4 Lymphocyte Count
  • Cidofovir
  • Cytomegalovirus Retinitis / etiology*
  • Cytosine / analogs & derivatives
  • Cytosine / therapeutic use
  • Drug Therapy, Combination
  • Ganciclovir / therapeutic use
  • HIV Infections / drug therapy*
  • Humans
  • Indinavir / administration & dosage
  • Lamivudine / administration & dosage
  • Male
  • Organophosphonates*
  • Organophosphorus Compounds / therapeutic use
  • Zidovudine / administration & dosage

Substances

  • Antiviral Agents
  • Organophosphonates
  • Organophosphorus Compounds
  • Lamivudine
  • Zidovudine
  • Indinavir
  • Cytosine
  • Cidofovir
  • Ganciclovir