Abstract
Initiation of transcription is the first step in gene expression and a major point of regulation. Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation.
MeSH terms
-
Animals
-
DNA-Directed RNA Polymerases / genetics*
-
Gene Expression Regulation, Bacterial / genetics
-
Humans
-
Molecular Structure
-
Promoter Regions, Genetic / genetics
-
Protein Structure, Tertiary / genetics
-
RNA, Messenger / biosynthesis*
-
RNA, Messenger / genetics*
-
Transcription Initiation Site / physiology*
-
Transcription, Genetic / genetics*
Substances
-
RNA, Messenger
-
DNA-Directed RNA Polymerases